Dr. Richard Peterson, Professor
Joined ERP Program: 1996
Department: Pharmacology, Faculty Profile
Address: 5109 Rennebohm Hall, 777 Highland Ave. Madison, WI 53706
Telephone: (608) 263-5453 FAX: (608) 265-3316
Email: repeterson@pharmacy.wisc.edu
Background:
| Institution | Degree | Year | Area of Study |
| University of WI-Madison | B.S. | 1967 | Psychology |
| Marquette University | Ph.D. | 1972 | Pharmacology |
Professional Experience:
| 1973-1975 | Instructor, Department of Pharmacology, Medical College of Wisconsin |
| 1975-1979 | Assistant Professor, School of Pharmacy, University of Wisconsin-Madison |
| 1979-1984 | Associate Professor, School of Pharmacy, University of Wisconsin-Madison |
| 1984-Present | Professor, School of Pharmacy, University of Wisconsin-Madison |
Honors and Awards:
1983-1988 |
NIEHS, Research Career Development Award |
| 1989-Pres | Editorial Board, Toxicology and Applied Pharmacology |
| 1993 | Society of Toxicology- Frank R. Blood Award |
| 1997-Pres | Board of Scientific Counselors, National Toxicology Program |
| 1998-Pres | Deputy Director, NIEHS Center for Developmental and Molecular Toxicology, University of Wisconsin |
| 1998-Pres | Expert Registry, NIEHS, NTP, Center for Evaluation of Risks to Human Reproduction |
| 2000-Pres | Board of Publications, Society of Toxicology |
Research Statement:
The goal is to determine consequences of perinatal TCDD exposure on prostate development in the C57BL/6 mouse and elucidate mechanisms involved. Specific aims. are to identify aberrant effects of TCDD on development of ventral (VP), dorsolateral (DLP), and anterior (AP) prostate, determine using AhR knockout (AhRKO) mice if these effects require AhR, determine critical periods for producing them, elucidate androgen dependent mechanisms for causing them, determine if TCDD acts directly on urogenital sinus (UGS) or prostate to inhibit development, determine if co-exposure to a natural AhR antagonist in human food, resveratrol, ameliorates TCDD disruption of prostate development, identify during the critical period TCDD responsive genes in UGS, determine using a dose response approach TCDD responsive genes in UGS that may be involved in TCDD inhibition of prostatic budding, and determine long-term consequences of perinatal TCDD exposure on prostate size, histology, and growth in senescence.
Former ERP Graduate Students:
- Kinarm Ko, PhD 8/03
Grant Funding:
| Funding Period | Project |
| 03/01/02 to 02/28/07 | R. Peterson (PI) COMM NOAA NA16RG2257 Sea Grant FY 2002 Dioxin Developmental Toxicity in Zebrafish |
| 06/21/04 to 05/31/07 | R. Peterson (PI) NIH 5 R01 CA095751-03 Ah Receptor Regulation of Prostate Tumor Progression |
| 02/01/05 to 01/31/07 | R. Peterson (PI) NIH 5 F31 HD049323-02 Inhibition of Fetal Prostate Development by Dioxin |
| 07/01/05 to 08/31/09 | R. Peterson (PI) NSF DMR-0425880 NSEC-SEED 4 Safety Assessment Of Nanomaterials In Zebrafish |
| 09/09/05 to 08/30/10 | R. Peterson (PI) NIH 5 R37 ES001332-31 Reproductive and Developmental Toxicity of Dioxin |
| 03/01/06 to 02/28/07 | R. Peterson (PI) COMM NOAA NA06OAR4170011 FY 2006-2008 Sea Grant Program -- Early Life Stage Exposure To 2,3,7,8- Tetrachlorodebenzo-P-Dioxin |
| 07/01/06 to 06/30/07 | R. Peterson (PI) NIH via UW-Milwaukee Marine and Freshwater Biomedical Sciences Center |