Dr. Elaine Alarid, Associate Professor
Joined ERP Program: 1999

Department: Oncology
Mailing Address: 710 Mcardle Cancer Research Bldg, 1400 University Ave., Madison, WI, 53706.
Telephone: (608) 265-9319   FAX: (608) 265-5512
E-mail: alarid@oncology.wisc.edu

Background:

Institution Degree Year Area of Study

University of California, Berkeley

B.A.

1985

Genetics

University of California, Berkeley

Ph.D.

1991

Physiology

University of California, San Francisco

Postdoc

1991

Anatomy

University of California, San Diego

Postdoc

1992-95

Reproductive Medicine

Professional Experience:

1985-1986  Laboratory Associate, Cetus Corporation, Emeryville, CA
1986-1991  Ph.D. Thesis research with Professor Charles S. Nicoll, Department of Physiology, University of California, Berkeley.
1991-1992 Postdoctoral Fellow with Professor Gerald Cunha, Deparment of Anatomy, University of California, San Francisco.
1992-1995 Postdoctoral Fellow with Professor Pamela Mellon, Departments of Reproductive Medicine and Neurosciences, University of California, San Diego
1995-1997 Assistant Scientist, Department of Biochemistry, University of Wisconsin-Madison
1997   Assistant Scientist, Department of Physiology, University of Wisconsin –Madison; Associate Scientist, Department of Physiology, University of Wisconsin-Madison
1998 - 2005 Assistant Professor, Department of Physiology, University of Wisconsin-Madison
2005-2006 Associate Professor, Department of Physiology, University of Wisconsin-Madison
2007-Present Associate Professor, Oncology Department, University of Wisconsin-Madison.

Honors and Awards:

  • New Mexico Chapter GI Forum Undergraduate Scholarship 
  • University of California Opportunity Fellowship, 1986, 1987, 1989
  • NRSA predoctoral training grant 1990
  • Initiative for under-represented minorities in biological sciences, RO1 supplement 1991. (Dr. G. Cunha)
  • Initiative for under-represented minorities in biological sciences, RO1 supplement 3/1/92-6/30/92. (Dr. P.L. Mellon)
  • Ford Foundation Postdoctoral Fellowship, 7/1/92-6/30/93
  • University of California President's Postdoctoral Fellowship, 7/1/92-6/30/94
  • NRSA postdoctoral training grant 7/1/94-6/30/96
  • Anna Julia Cooper Award 7/97
  • Howard Hughes Medical Institute/ University of Wisconsin Faculty Development Award 2000

Research Statement:

The research in our laboratory focuses on dissecting the molecular mechanisms controlling estrogen responsiveness in the female reproductive system. Estrogen mediates its actions through its receptor, estrogen receptor (ER), a member of the nuclear receptor family. Members of this family are key molecular targets in the pharmacological intervention for diseases including breast and prostate cancer, diabetes, cardiovascular disorders, metabolic X syndrome and osteoporosis, among others. Disregulation of ER is prominent in common reproductive pathologies such as breast cancer and infertility where it is often expressed at levels above those of normal tissues. We are pursuing research into the control of cellular levels of ER by estrogen with emphasis on transcriptional, translational and post-translational mechanisms. Our research incorporates models of steroid signal transduction pathways, and basic mechanisms of transcription.

Current Grant Funding:

Funding Period Project
04/01/04 to 02/28/08

Alarid (PI) NIH R01 NIDDK "Proteolytic Regulation of Estrogen Receptor" "
Award Number: 5 R01 DK064034-03
09/15/06 to 09/14/09

Transcriptional Repression of Estrogen Receptor-Alpha In Breast Cancer Cells (Ellison, Stephanie - Pre-Doc)

Representative Publications from Dr. Alarid's Lab Search PubMed