David H. Abbott, PhD

Faculty PhotoEmail: abbott@primate.wisc.edu
Title: Professor
Department: Obstetrics & Gynecology
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Trainees
PubMed Publications

Education

BSc 1975 University of Endinburgh, Edinburgh, Scotland
PhD 1979 University of Edinburgh, Edinburgh, Scotland
1st Postdoctoral Position: University of Wisconsin-Madison

Research Focus

I have over 30 years of experience employing animal models of female reproductive endocrinology to determine pathophysiological mechanisms underlying a variety of reproductive health disorders commonly found in women. More recently, in collaboration with Dr. Dumesic (Co-I in this application), my lab developed a comprehensive nonhuman primate model for polycystic ovary syndrome (PCOS) that was the vanguard for a multitude of animal and human studies aimed at determining developmental origins of this most common endocrinopathy in women. We have translated insight gained from the nonhuman primate model to discern pathophysiological mechanism causing discrete aspects of reproductive and metabolic dysfunction in women with PCOS, including abnormalities at the molecular level. Our most recent work identifies metabolic dysfunction as possibly the initial abnormality in early developmental origins of PCOS.

Program Activities

  • Joined ERP Program: 1993
  • Teaching
    • Animal Sciences 875: Endocrine Physiology
    • Animal Sciences 875: Reproductive Patterns

Research Funding

Trainees

Current Trainees Degree Goal
Beverly Hutcherson MS
   
Past Trainees Degree Completed
Joel Eisner PhD
Rao Zhou PhD